News

Mitochondrial Disease Signaling Network Discovered

Children’s Hospital researchers recently identified a network of signaling molecules that acts like a “fuse box,” regulating the effects of defective energy flow in mitochondrial respiratory chain diseases — a set of difficult-to-treat genetic-based energy disorders. Using that knowledge, they showed that a form of vitamin B3 partially restores normal functioning in cells taken from patients with mitochondrial disease.

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Effectiveness of Decision Support for Families, Clinicians, or Both on HPV Vaccine Receipt.

Despite proven health benefits, human papillomavirus (HPV) vaccination rates are among the lowest of all routine immunizations. No previous large-scale trial has compared the benefit of automated decision support directed at clinicians, families, or both in any context.

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Male-biased autosomal effect of 16p13.11 copy number variation in neurodevelopmental disorders.

Copy number variants (CNVs) at chromosome 16p13.11 have been associated with a range of neurodevelopmental disorders including autism, ADHD, intellectual disability and schizophrenia. Significant sex differences in prevalence, course and severity have been described for a number of these conditions but the biological and environmental factors underlying such sex-specific features remain unclear.

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Web of Autism Genes Pinpoints Key Players

Hundreds of genes have been linked to autism, but to understand the roles they play – and the ones most likely to eventually lead to treatment – we need to work out how they are connected to one another.

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CBMi's Stacey Wrazien Wins REDCap 'Interesting Use Case' for Second Year in a Row

CBMi's Stacey Wrazien was selected as one of three winners for "Interesting Use Case' at REDCap Day 2013. Her presentation "The Data Almanac" a web application that allows users to create, collect, and track standards associated with electronic case report forms.

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Dr. Alexander Fiks Wins 1st Place in AHRQ PBRN Vaccine Manuscript Contest

Congratulations to Dr. Alexander Fiks - 1st Place Winner - AHRQ PBRN Vaccine Manuscript Contest.

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Congratulations to First Graduating Class - Post-Bac Health Informatics Certificate

Congratulations to the first graduating class for Temple's Post-Bac Healthcare Informatics Certificate.  Graduates include:
Francesca Almond, Elena Becker, Susan Becker, Carol Ann Gelder, Amina Khan, Linda Murray, Edward Ojuok, Lillie Rizack, Mary Schucker, Peretz Wittman

Earn Your Temple Post-Bac Health Informatics Certificate. Submit your application by July 30, 2013 for the Next Class Starting in the Fall of 2013. Classes will take place on the CHOP campus.

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Art Drawn from the 6th Annual Mid-Atlantic Healthcare Informatics Symposium

Regina Holliday is an activist, artist, speaker and author in Washington DC. She participated in the Patient engagement panel at the 6th Annual Mid-Atlantic Healthcare Informatics Symposium on April 26, 2013. Not only was she a very engaging speaker but she also painted the content she hears from the patient view. You can read more and see the paintings she created at our symposium in her blog "Regina Holliday's Medical Advocacy Blog."

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Philadelphia Hospitals’ Informatics Teams Target Sepsis Response

Sepsis, a dangerous condition caused by the immune system’s response to a serious infection, is one of the toughest challenges hospitals face. It causes 17 percent of all hospital deaths and is the leading cause of death in non-cardiac intensive-care units. Additionally, the incidence of sepsis is increasing in the United States. But healthcare informatics researchers are working on ways to quicken response times and improve outcomes. Two presentations by CBMi's Dr. Robert Grundmeier and medical candidate Katherine Clark from the University of Pennsylvania's Perelman School of Medicine presented at the 6th Annual Mid-Atlantic Healthcare Informatics Symposium are discussed in Healthcare Informatics Online.

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CBMi pediatricians talk about health IT innovations for vaccines asthma

Doctors Robert Grundmeier and Alexander Fiks at the Center for Biomedical Informatics at CHOP talked about the Care Assistant program at a recent health IT seminar at the Quorum at the University City Science Center. It was originally designed as a tool to do more precise decision-support projects to improve healthcare outcomes using the provider’s electronic health record system from Epic.

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